Jonathan Rosand, MD, MSc

Harvard University

Jonathan Rosand is Professor of Neurology at Harvard, where he is appointed to the J P Kistler Endowed Chair in Neurology at Massachusetts General Hospital and serves as Associate Member of the Broad Institute of MIT and Harvard. An internationally renowned scientist, clinician, educator and administrative leader, he has created a legacy of multidisciplinary teams that are successfully tackling some of the most pressing challenges in brain disease.

The author of over 300 scientific publications, Rosand with his lab conducts research in partnership with thousands of volunteer patients and families to prevent strokes and improve recovery from stroke and other brain injuries. Their focus is discovering the role of genetics and using those discoveries to speed up the development of new treatments. The lab is a leading contributor to the performance and analysis of high-throughput genome-wide association and sequencing studies in stroke and related traits. In order to accelerate these discoveries, Jonathan founded the International Stroke Genetics Consortium to bring together the world’s pre-eminent stroke investigators, and launched the NIH-funded Platform for Accelerating Genetic Discovery for Cerebrovascular Disease to share data widely. The Consortium is now composed of over 70 investigators from 6 continents who work collaboratively on an unprecedented scale and publish their work in the world’s leading journals.

Jonathan has trained a generation of national leaders in neurocritical care, stroke and clinical investigation. He served as Program Director for Harvard’s clinical training programs in both stroke and neurocritical care, and is Principle investigator of the NIH investigator training program Recovery and Restoration of Central Nervous System Health and Function After Injury. His lab has been the training ground for outstanding investigators who have gone on to establish their own independent research programs at top academic institutions in the US and abroad. Jonathan directed the National Institute of Neurological disorders and Stroke-American Neurological Association annual training course for 6 years and has served as Chair of the NINDS Study Section responsible for peer review of K applications. 

After founding Mass General’s Division of Neurocritical Care, recruiting and mentoring a dozen faculty, and building it into the nation’s top program, Jonathan stepped down to establish the Henry and Allison McCance Center for Brain Health with colleagues from neuroscience and psychiatry. Grounded in his experiences with patients and families and the results of his research as well as that of his colleagues, the mission of the McCance Center is to develop the tools to prevent brain disease from ever occurring in the first place and preserve brain function across the lifespan. Through innovative clinical care, research and multidisciplinary collaboration, the McCance Center aims to achieve for brain disease what has been achieved for heart disease over the past 60 years and thereby bring the brain health-span to match the lifespan. Jonathan cares for patients in the Neuroscience Intensive Care Unit and the McCance Center’s outpatient practice.