Gregory Wu, MD, PhD

Washingington University St. Louis

Dr. Wu was born and raised in Iowa. He graduated from Washington University in St. Louis with a B.A. in Biology before returning to Iowa to obtain his MD and PhD degrees. He received his MD and PhD degrees as a part of the NIH Medical Scientist Training Program at the University of Iowa. His PhD thesis work under the mentorship of Dr. Stanley Perlman investigated the mechanisms of virus-induced central nervous system demyelination. While a graduate student, he was a recipient of a National Research Service Award (F30) from the NIH. Dr. Wu began his post-graduate medical education as an intern in Internal Medicine at the Mount Sinai School of Medicine. Subsequently, he completed a Neurology residency in 2005 at the Hospital of the University of Pennsylvania. During his residency he was awarded a Penn Pearls Award in recognition of his excellence in medical student education. He received several awards from the North American Neuro-Ophthalmology Association for research on visual outcome studies in multiple sclerosis led by Dr. Laura Balcer. Following residency, Dr. Wu trained as a Multiple Sclerosis fellow at the University of Pennsylvania. He received a National Multiple Sclerosis Society postdoctoral fellowship from 2005-2008, which supported postdoctoral research training in autoimmunity under the guidance of Dr. Terri Laufer at the University of Pennsylvania. In 2008 he was the recipient of a K08 career development award from the NIH for his work investigating the role of dendritic cells in an animal model for MS. That same year he was appointed instructor in the department of Neurology at the University of Pennsylvania. In 2009 Dr. Wu moved to Washington University in St. Louis to establish his own laboratory. Since then, he has obtained independent funding from the NIH, Doris Duke Charitable Foundation, Dana Foundation, National Multiple Sclerosis Society, and various other private entities. The mission of the Wu lab is to define the mechanisms involved in the regulation of immune responses within the central nervous system. Current work explores how B cell antigen presentation propagates inflammation in multiple sclerosis, the role of Vanilloid channels in innate immune cell function, and correlates between immune and MRI changes in multiple sclerosis. "

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