Afsaneh Shirani, MD, MSCI

University of Nebraska Medical School

Afsaneh Shirani, MD, MSCI is an Assistant Professor in the Division of Multiple Sclerosis of the Department of Neurological Sciences at the University of Nebraska Medical Center in Omaha. She obtained her MD degree at Tehran University of Medical Sciences in Iran following which she joined the University of British Columbia, Vancouver, Canada as a post-doctoral research fellow under the supervision of Dr. Helen Tremlett, focusing on investigating the long-term impact of beta-interferons on MS disability progression in the real-world practice setting, as well as other MS-related pharmaco-epidemiological projects. She also benefited from Dr. Emmanuelle Waubant’s mentorship during a short-term research visit at University of California, San Francisco. Afsaneh moved to Texas in 2013 for neurology residency training at University of Texas Southwestern Medical Center in Dallas where she remained actively involved in MS research under the mentorship of Dr. OIaf Stuve and Dr. Darin Okuda. Passionate about how neuroimaging can be used as a translational tool to pave the way toward a personalized medicine approach in MS, she joined Washington University in St. Louis for her post-residency fellowship under the primary mentorship of Dr. Anne Cross, and co-mentorship of Dr. Sheng-Kwei (Victor) Song. She focused on investigating the biomarker potential of a novel imaging method called diffusion basis spectrum imaging (developed at Washington University) to differentiate and quantify MS pathologies using non-invasive imaging, and to predict long-term disability progression in people with MS. She also obtained a Master of Science in Clinical Investigation at Washington University. Afsaneh has been the recipient of a number of prestigious awards, such as the Clinician Scientist Development Award from the US National MS Society, Physician-Scientist Training Program Award from the University of Nebraska Medical Center, Clinical Research Training Scholarship from the American Academy of Neurology, Post-doctoral Fellowship Award from the MS Society of Canada, Jacqueline Du Pre Award from the MS International Federation, etc. Her research interests include neuroimaging biomarkers in MS, drug effectiveness and precision medicine, and strategies for promoting neurorepair and neuroprotection in the central nervous system of people with MS.